Tag : adrenal

In our last blog we talked about Cholesterol and Heart Disease. We discussed how the dangerous build-up of plaque is a result of low-density lipoprotein, or LDL cholesterol, becoming damaged or oxidized in the bloodstream. The body treats this oxidized LDL as a threat, and sends white blood cells to attack the cholesterol. In order to reduce the threat of heart disease, we have to prevent plaque from forming. There are three major ways to accomplish this.

The first way to reduce plaque build-up is to reduce the amount of LDL cholesterol available to be oxidized in the first place. Reducing cholesterol is the focus of most of our traditional efforts at preventing heart disease.  Cholesterol reduction is the primary reason so many millions are on statin drugs like Lipitor.

Are clinical trials using animal studies always valid for humans? Consider me a skeptic.

I frequently see advertisements and newsletters (even some written by physicians) that promote lab tests and treatments based entirely on studies done using rodents. These “experts” frequently draw conclusions from these studies that their lab test or product is a breakthrough of vital importance to humanity. While it may be true, all too often it’s not.

Let me give you a recent example of a study done in mice that could lead to the conclusion that every woman with breast cancer should be taking very robust doses of the adrenal hormone DHEA. This study should serve both as an encouragement and as a caution, an example of the care we must exercise when we use animal studies to draw conclusions about humans.